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Prostate Cancer


A current estimate is that one in every six men in the United States will be diagnosed with prostate cancer.

The most important supplements are : JIPANG Ginger, Omega Plus Revolution, Magnesium, Selenium, Vitamin B12, Inositol, Vitamin K2

With the exception of rare variants (small cell carcinoma, squamous cell carcinoma), prostate cancer is one of the easiest cancers to cure. This success in treatment is largely due to advances in surgery, radiotherapy, brachytherapy, and cryotherapy. Despite these improvements, there is an increased risk, albeit minimal, of erectile dysfunction (impotence) and incontinence in the wake of surgery or radiation therapy.

If surgery and radiation don't cause impotence, hormone therapy ultimately leads to erectile dysfunction, and eventually prostate cancer cells become hormone refractory. For men with preexisting heart problem, androgen-deprivation therapy increases the possibility of developing vascular disorders. Patients receiving chemotherapy can have serious side effects, affecting healthy cells and the immune system. Watchful waiting, also known as expectant management, is a reasonable strategy for men in their 70s or older, but for those under 70, that approach may be less appropriate. What is needed are more efficacious, safer, and noninvasive therapies for prostate cancer. A barrier is the limitations of what we know about the underlying mechanisms that drive prostate cancer and, like all cancers, various signaling pathways, proteins and genetic aberrations are involved, a complex process at best.

One theory is that prostate cancer is fueled by testosterone. However, very young men usually have a greater amount of free testosterone than older men, but rarely suffer from prostate cancer. Excess estradiol, converted from testosterone by aromatase, also plays a role in the development of prostate cancer. The hypothalamic-pituitary-gonadal axis, which controls embryonic development, reproduction and aging, is also involved. Gonadotropin-releasing hormone (GnRH) is manufactured by the hypothalamus, whereas luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are produced by the anterior part of the pituitary gland, and the gonads produce estrogen and testosterone. LH stimulates the production of testosterone and estrogen in testicular Leydig cells. The prostate cancer picture is further embellished by two enzymes, 5-lipoxygenase (5-LOX) and aromatase. 5-LOX is critical in the synthesis of leukotrienes from arachidonic acid, and exacerbates prostate cancer. 5-LOX converts arachidonic acid into 5-hydroperoxyeicosatetraenoic acid (5-HPETE), which is spontaneously reduced to 5-hydroxyeicosatetraenoic acid (5-HETE). 5-HETE is a fatty acid that abrogates apoptosis, or the death, of prostate cancer cells. Aromatase converts testosterone to estradiol, which in excess amounts is carcinogenic.

Thus, to tackle prostate cancer, novel therapies must fulfill various roles, including enhancing immunity, regulating hormone dysregulation and enzymatic activity. A supplement already exists that can address these mechanisms. Shell Ginger (Alpinia zerumbet) improves immunity and re-establishes hormonal and enzymatic homeostasis, or balance. The leaves of Shell Ginger have been long used to prepare a tea, which is commonly drunk by the people of Okinawa, who have one of the longest life spans in the world.
I discovered the medicinal properties and activities of Shell Ginger. For the past 30 years, I have traveled to more than 85 countries in my quest to discover natural substances that can improve human health. This effort led me to identify the most effective and safest herb for treating prostate cancer, JIPANG Ginger, whose main active ingredient is derived from the fermented leaves of Shell Ginger.

Although Shell Ginger grows in only a few places in the world, the variety grown on the remote Japanese islands of Okinawa, the key ingredient in JIPANG Ginger, is best of all, because the soil there is distinct, composed of weathered coral limestone. That makes the pH level of the soil weakly alkaline, which is the optimal physiological condition for maintaining internal health. Plants get energy by photosynthesis, which releases reactive oxygen species. The stronger the sunlight is, the more free radicals are produced, requiring plants to adopt compensatory mechanisms for protecting their leaves and stalks. I and my research team discovered the fact that the variety of Shell Ginger grown in Okinawan soil is packed with dozens of polyphenols, such as ferulic acid, chlorogenic acid, quercetin, kaempferol, epicatechin, catechin, and others. These polyphenols act synergistically to become powerful natural antioxidants with the ability to protect normal human cells.

Omega Plus Revolution is a very unique oil that is a blend of Flaxseed Oil, Camellia Japonica Seed Oil, and Pine Needle Oil.
Together this powerful combination of oils will support your immune system and body’s natural anti-inflammatory response.
The benefits of the omega 3 unsaturated fatty acids are well known. But did you know over the long term, regular consumption of omega supplements may not be good for you? And that the oils could be harming you instead of helping you? Why? Because these polyunsaturated fats are extremely heat and oxygen sensitive. Meaning the oils will easily oxidize and turn rancid in your blood stream, this is much more harmful than animal fat.
If you are taking standard omega 3 supplements such as ordinary flaxseed oil or fish oil, it's time to reconsider it. A large percentage of ALA (alpha-linolenic acid) and EPA(eicosapentaenoic acid), DHA (docosahexaenoic acid) becomes oxidized within 24 hours of entering your blood stream. When this happens lipid peroxidation takes place which results in very large amounts of free radicals floating around your body causing the scarring of cell membranes and this is very dangerous.
The two oils, Camellia Japonica Seed Oil and Pine Needle Oil, slow down the oxidation process of omega 3 fatty acid of flaxseed oil in the blood stream.
If it is not possible to get Omega Plus Revolution in your country, please write to me (dr@drmakise.com) . Or flaxseed oil can substitute for it.
* One caveat is that olive oil should NOT be used as the substitute and should not be used at all by cancer patients.

My prescription for treating prostate cancer is:

JIPANG Ginger 6-8 capsules/day
Omega Plus Revolution  3 capsules/day
Magnesium (preferably magnesium glycinate)   200mg
Selenium 200 mcg
Vitamin B12
Vitamin K2
5000 mcg/day
50 mg/day
5 mg/day

Caution : Other vitamins and minerals should NOT be taken with my anti-prostate cancer formula shown in the table above.
The reason is as follows;
Cancer cells are by nature fairly clever entities because of their ability to escape from capture and annihilation by the immune system and continue to propagate. They are so clever that when they become resistant to traditional therapies, which they almost always do when the patient lives long enough, they are able to spread cancer to other parts of the body, or transmutate into different types of tumors. Among their bag of clever tricks is their ability to use various vitamins and minerals that people take to destroy cancer cells or to allay their development in the first place, and instead paradoxically use the vitamins and minerals to grow and metastasize. Cancer cells are avaricious and opportunistic, so we must be very careful not to fuel them by taking too many different supplements.
For example, according to the study of Jane C. Figueiredo, PhD, of the University of Southern California, Los Angeles, "Folic Acid and Risk of Prostate Cancer: Results From a Randomized Clinical Trial", folic acid supplementation was associated with an increased risk of prostate cancer. Vitamin C is no exception. The danger exists that cancer cells utilize vitamin C to grow. Thus, the commonly utilized mega dose vitamin C therapy is quite controversial and its benefits are moot.
Some people have asked why my prescription does not contain lycopene, zinc, saw palmetto, beta-sitosterol. While these substances can be effective in treating benign prostatic hyperplasia, (BPH), they are ineffective against prostate cancer, with the exception of beta-sitosterol, which is already contained in Shell Ginger. Lycopene has long been touted as a natural and effective remedy for prostate cancer, and it is if it is ingested from whole tomatoes. The concentrated extract of lycopene, on the other hand, is dangerous, similar to beta-carotene supplementation. Supplemental β-carotene has been associated with an increased risk of prostate cancer, cardiovascular disease and overall mortality in people who smoke cigarettes. The possibility exists that this danger extends to non-smokers. Lycopene is a carotenoid and too much of it is simply not safe, however, no one knows how much is too much.

Although Magnesium, Selenium, Vitamin B12, Inositol, Vitamin K2 are available at any vitamin shops,
JIPANG Ginger and Omega Plus Revolution may be not easy to find. If so, please open

Dr. Makise - After following your protocol of JIPANG Ginger and flax for 2 months, my PSA has fallen from 62 to 29. Hopefully, the next two months will have it down to 0. I'm down to my last bottle of JIPANG Ginger. I called your number and they said they were out of the product. Could you see that I get some more before I run out? Thank you.

I used the JIPANG Ginger to help me survive prostrate cancer. It worked very well. I am now cancer free. I know of other people that are now contacting me with inoperable forms of terminal cancer. I was hoping they would be able to purchase the ginger to start taking and at least give them some hope. Please let me know if they will be able to purchasE directly from you. Thank you.


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