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Essential Supplements 3-4

Therapeutic Prescriptions by Vitaminx & Minerals

This is information obtained from Dr. Makise's having cured atopic dermatitis of 40,000 people or more in total and the latest and highest atopic dermatitis treatment. But this is provided for information only. No action should be taken based solely on the contents of this website; instead, readers should consult appropriate health professionals on any matter relating their health. Readers who fail to consult with appropriate health authorities assume the risk of any injuries. Dr. Makise is not responsible for errors or omissions.
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3. Vitamin B12:1000µg/Day

This vitamin has a red color, and is a multi-atom complex containing a cobalt atom in the middle of its structure. This was discovered as a result of researching whether the liver of animals could help people with malignant anemia. This vitamin is especially effective in treating AD by eliminating nitric oxide (NO). Nitric oxide is a type of free radical and if there is an excess amount, it could damage many organs, including the skin. Also, it can be a skin inflammation mediator and can worsen skin inflammation, which is the basis of AD.
Supplements that claim to eliminate active oxygen, such as superoxide, hydroxy radical, hydrogen peroxide, and singlet oxygen, are not enough. You must also eliminate excessive nitric oxide.

As I have mentioned before, at my clinic we mix this vitamin with ointments. You should also take these orally. However, the Recommended Dietary Allowances set forth by the Japanese Ministry of Health, Labour, and Welfare is 2.4 micrograms per day, which is clearly not enough for AD treatment. There will be no effect unless you take 1000 micrograms, nearly 500 times the recommended amount.
You may wonder whether there will be some side effects if you take that much, but I can assure you that there are absolutely no side effects. Also, some doctors and specialists say that overconsumption of Vitamin B12 will mislead megaloblastic anemia diagnostics, but rarely do people get this disease, and in my 30 years of being a doctor, I have never seen a patient with this disease (even when I was an intern at a university hospital). To not allow large consumptions of Vitamin B12 to treat AD, which, these days, afflicts more than 20% of all elementary school children is appalling, because doctors claim that it will hider the diagnosis of an extremely rare disease.

4. Other members of the Vitamin Bs

Vitamin B12 will be more effective when taken with other type B vitamins. Vitamin B1, B5, B2, and B6 all of which have unique effects when used for AD treatment.

Vitamin B1:50mg/Day、Vitamin B5(pantothenic acid):50mg/Day
These two vitamins will make the adrenal cortex more active when combined with Vitamin C. In the adrenal cortex, cortisol (a type of steroid hormone) is produced. It is well known that this hormone subdues allergies. When AD symptoms suddenly get worse, there are some times when I am forced to prescribe steroids such as predonine. However, rather than supplemented steroids, the steroid hormones made in your adrenal gland are safer. These vitamins aid the production and secretion of these safe steroids, so it is strongly recommended that you take them. If you use them with vitamin C, you can generate a synergetic effect.

Vitamin B5 is also a key ingredient in coenzymes, which are necessary in the most important reactions in the body such as the citric acid cycle and β-oxidation, so it is necessary to supplement this vitamin. It is also effective in detoxifying toxic substances from the body. You can read a section on detoxifying later on. It is also effective, like zinc, at controlling herpes, a common disease for AD patients.

Vitamin B2:50mgDay, Vitamin B6:50mg/Day
These two reduce the redness of the face seen in many AD patients. Patients in their teens, in particular, get upset over this problem.
Patients will fret over skin redness that others may not even notice. It is actually better to inject B2 and B6, but it is not realistic to advise people to go to the hospital every day unless you are being hospitalized. In that case, you can take them orally, but be sure to take them in large quantities. Since they are soluble, you don’t need to worry about an overdose. These vitamins do not work for everyone, so try for 3 months at first. B6, along with manganese, is necessary for the production of ceramide, which I have explained in section 6 “On Dry Skin”. It is also a key ingredient in the production of cysteine, an amino acid that takes out mottles and brightens skin. ( However, nursing mothers or pregnant women should not take over 25 mg of Vitamin B6 per day. B6 reduces the secretion of prolactin, a lactogenic hormone)

Cysteine can also be effective in reducing redness. Try using 1000 to 2000 mg per day.

Vitamin B2 is also called riboflavin, and is important to the thyroid gland and can cause dermatitis and glossitis when there is a deficiency. B2 and B1 can be found in pork and bowels, but since AD patients should not eat meat, many develop type B deficiencies. This is why it is necessary to get these vitamins from supplements.


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