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Is Cholesterol a Villain? (1/5)

 

Is Cholesterol a Villain?

No, not at all! Cholesterol is not a villain. Cholesterol is our good friend, because it is very important for a lot of physiological functions.

In the first place, you must understand that lipids such as cholesterol and triglyceride
themselves do not do any harm. Even if a large amount of pure cholesterol is injected into experimental animals, atherosclerosis will not occur. Nonetheless, when total cholesterol level is only 220 mg/dl or more, or triglyceride is more than 150 mg/dl, or LDL is more than 140 mg/dl, doctors will prescribe antihyperlipidemic drugs.

Especially HMG-CoA reductase inhibitors (so-called statin-based drugs - pravastatin, simvastatin, atorvastatin, fluvastatin, etc.), which are prescribed the most often in the United States, Japan, and Europe, have serious drawbacks. It has a side effect of exhausting CoQ10 in the body. If you are taking medications of statin-based
antihyperlipidemic drugs, such as mevalotin, lipovas, zocor, lipitor, livalo etc, be sure to take CoQ10 (reduced type). Because statin drugs exhausts CoQo10 that is very important coenzyme for the heart.
If you would like to know more, please refer to the following article. You would understand why you need to take CoQ10 supplement very much as far as you are on statin drugs. Even 400 mg of CoQ10 is not sufficient.
(Rundek, T., et al. Atorvastatin decreases the Coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke.
Arch Neurol.2004 June;61(6):889-92)

CoQ10 is not only an important antioxidant but also a very important coenzyme for the proper functioning of the heart. However, the antihyperlipidemic drug themselves which is taken to prevent angina pectoris and myocardial infarction has the effect of depleting the essential nutrient CoQ10 in myocardium. Moreover, statins based
antihyperlipidemic drugs have a very serious side effects called rhabdomyolysis.
https://en.wikipedia.org/wiki/Rhabdomyolysis

If you have never suffered from CHD (coronary heart disease) such as myocardial infraction or angina pectoris in the past, or if you are not diabetics now, you do not need to take especially any statin based antihyperlipidemic agents. Even if your cholesterol is 280 mg/dl, not necessary. Rather, that much cholesterol is just appropriate. Those who have such amount cholesterol are less prone to cancer and also less prone to depression. At least as for Japanese, lesser the total cholesterol and triglyceride, the higher is the total mortality rate. For those who are obsessed with wanting to reduce the level of cholesterol and triglyceride, it is safe to lower with supplements. (However, excluding the cases when you have abnormal thyroid function, diabetes, side effects due to chemicals, kidney diseases, etc.)


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