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Topical Steroid Ointment

Therapeutic Prescriptions by Vitaminx & Minerals

This is information obtained from Dr. Makise's having cured atopic dermatitis of 40,000 people or more in total and the latest and highest atopic dermatitis treatment. But this is provided for information only. No action should be taken based solely on the contents of this website; instead, readers should consult appropriate health professionals on any matter relating their health. Readers who fail to consult with appropriate health authorities assume the risk of any injuries. Dr. Makise is not responsible for errors or omissions.
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(Ⅰ) Topical Steroid Ointment

The biggest concern of current Atopic Dermatitis (AD for short) patients is topical steroid use, which, if used over time could cause skin inflammation and atrophy. Steroids causes IL-1, an inflammatory cytokine that causes cornification cell of the skin, which induces dermatitis, while the action of fibroblasts, which produce new skin cells, are suppressed and this starts atrophy of the skin.
As a result, a little stimulation easily breaks the skin, and the resulting serious itch makes patients scratch their skin so hard that they start to bleed. Moreover, topical steroids gradually lose their effectiveness, forcing patients to use stronger steroids in a larger quantity. Therefore, we will tend to avoid using topical steroids for a patient’s treatment.
However, it is also quite foolish not to use topical steroids at all out of fear. The adverse drug reactions to orally taken steroids include a variety of symptoms such as hypertension, moon face, gastric ulcer, diabetes mellitus, psychosis, cataracts, decreased immunity, and osteoporosis. If steroidal ointment is applied to the skin, a patient shouldn’t worry about these side effects. In order to have the same adverse drug reaction induced by oral steroids, patients must use an exorbitant amount of steroidal ointment on the skin. Everyday application of two 10-gram-tubes of the strongest steroidal ointment such as Dermovate or Diflar all over the body for 1 month will only bring about at most the same amount of absorption of the steroid hormone into the body as when 1 tablet of Predonine (prednisolone) is orally administered. This makes it virtually impossible for the application of topical steroidal ointments to bring about the same side effects induced by oral steroids.
You may find some dermatology textbooks that claim the application of steroidal ointments on the surroundings of the eyes brings about cataracts, but at this point this is only a theory and is not a clinical fact. Although AD patients tend to suffer from cataracts, amotio retinae, and corneal ulcer (in which case I strongly recommend patients to undergo periodic ophthalmologic checks) these ophthalmologic problems are not induced by the adverse side effects of topical steroid ointment. Since skin and eyes are developed from the ectoderm at the embryonic stage, they are sensitive to oxygen radicals due to their same biological origin. In addition, patients scratch the surroundings of their eyes to calm to itch on their face, which intensifies skin irritation around the eyes. Moreover, although it is said that topical steroid ointment causes pigmentation, pigmentation is actually caused by inadequate treatment and failure to control the inflammation of the skin, not by topical steroid ointment.
If topical steroidal hormones are used over a long time, the body will strengthen the action of the inflammatory cytokine, IL-1, and induce skin inflammation. When the action of fibroblasts, which produce the new skin cells, is stunted, atrophy of the skin emerges. Many AD patients will bleed all over their body since their skin itches, which makes patients scratch and tear their sensitive skin. However, this will only happen if patients use steroidal hormones for months to years. Short-term topical usage of steroids will not cause these problems, and thus steroid ointment will be used only in short time periods.
You must keep in mind that it is wrong to apply topical steroid ointment on the skin if you do not show AD symptoms. Doctors and hospitals recommend patients to use topical steroid ointment “for relapse prevention” or “perseveringly”. However you must be cautious since the more ointment a patient uses, the more money the doctors and hospitals will get; they may just be greedy.
Instead, for relapse prevention, use steroid-free ointments.
There are some patients who suffered skin atrophy and inflammations after long-term usage of topical steroid ointment. These patients usually try to stop using topical steroid ointment several times, but rebound and use steroids again. This should not discourage anybody; through alimentary therapy, vitamin-mineral supplements, detoxication treatments, and small changes in lifestyle, it is possible to withdraw from steroids. Although it sounds paradoxical, my patients use topical steroid ointment effectively to promptly withdraw from steroids.
Caution: Some doctors give intramuscular injections of Kenacort (chemical name: trimacinolone acetonide) to their patients for withdrawal from topical steroid ointment. This is more dangerous because it is an injection. If such treatment is used, you must fear the adverse drug reaction of steroids since Kenacort consists of steroid hormones.
Neither Kenacort ointment nor the Kenacort lotion has a problem. However, injection is different from ointment and lotion. You must be especially alert if an injection makes the symptoms of AD disappear quickly since the injection might have contained steroids. Please ask the doctor for more information in these cases. Moreover, although the ointment contains steroids, sellers claim that the ointment is steroid free. Please do not be fooled and do not use any ointments from China.


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